《Iron-catalyzed hydrosilylation of diacids in the presence of amines: a new route to cyclic amines》 was published in ChemCatChem in 2020. These research results belong to Wei, Duo; Netkaew, Chakkrit; Wu, Jiajun; Darcel, Christophe. Application of 4048-33-3 The article mentions the following:
Herein, a novel chemoselective strategy for building N-substituted cyclic amines I (n = 1, 2, 3; R = H, 4-Me; R1 = cyclohexyl, 1-(naphthalen-1-yl)ethyl, 2H-1,3-benzodioxol-5-yl, etc.) and 2-(4-methoxyphenyl)-2,3,3a,4,7,7a-hexahydro-1H-isoindole via iron catalyzed one-pot hydrosilylation starting from readily available dicarboxylic acids e.g., pentanedioic acid and amines R1NH2, with hydrosilanes as the hydride sources was presented. The described methodol. allows the preparation of a wide range of N-alkylated and arylated cyclic amine derivatives I (including pharmaceuticals Fenpiprane and Prozapine) in moderate to excellent yields, starting from inexpensive succinic, glutaric, and adipic acids with di-Me carbonate as a green solvent. In the experimental materials used by the author, we found 6-Aminohexan-1-ol(cas: 4048-33-3Application of 4048-33-3)
6-Aminohexan-1-ol(cas: 4048-33-3) may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties. It can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine.Application of 4048-33-3
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