Kawelke, Steffen’s team published research in PLoS One in 2015 | CAS: 591-70-8

Octadecan-9-ol(cas: 591-70-8) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains. The creation of a peptide bond to link two amino acids to make a protein removes the −OH from the carboxy group of one amino acid.SDS of cas: 591-70-8

The author of 《Two predicted transmembrane domains exclude very long chain fatty acyl-CoAs from the active site of mouse wax synthase》 were Kawelke, Steffen; Feussner, Ivo. And the article was published in PLoS One in 2015. SDS of cas: 591-70-8 The author mentioned the following in the article:

Wax esters are used as coatings or storage lipids in all kingdoms of life. They are synthesized from a fatty alc. and an acyl-CoA by wax synthases. In order to get insights into the structure-function relationships of a wax synthase from Mus musculus, a domain swap experiment between the mouse acyl-CoA:wax alc. acyltransferase (AWAT2) and the homologous mouse acyl-CoA:diacylglycerol O-acyltransferase 2 (DGAT2) was performed. This showed that the substrate specificity of AWAT2 is partially determined by two predicted transmembrane domains near the amino terminus of AWAT2. Upon exchange of the two domains for the resp. part of DGAT2, the resulting chimeric enzyme was capable of incorporating up to 20% of very long acyl chains in the wax esters upon expression in S. cerevisiae strain H1246. The amount of very long acyl chains in wax esters synthesized by wild type AWAT2 was negligible. The effect was narrowed down to a single amino acid position within one of the predicted membrane domains, the AWAT2 N36R variant. Taken together, we provide first evidence that two predicted transmembrane domains in AWAT2 are involved in determining its acyl chain length specificity.Octadecan-9-ol(cas: 591-70-8SDS of cas: 591-70-8) was used in this study.

Octadecan-9-ol(cas: 591-70-8) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains. The creation of a peptide bond to link two amino acids to make a protein removes the −OH from the carboxy group of one amino acid.SDS of cas: 591-70-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts