Quality Control of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraolOn June 4, 2020, Xie, Huijun; Chen, Xiaoyu; Li, Miaomiao; Aisa, Haji Akber; Yuan, Tao published an article in Tetrahedron Letters. The article was ãAngustifolinoid B, a flavonoid glycoside dimer with cyclobutane from Elaeagnus angustifolia flowersã? The article mentions the following:
A novel flavonoid glycoside dimer with an unprecedented cyclobutane moiety, named angustifolinoid B (1), was isolated from Elaeagnus angustifolia flowers. Its structure was determined by extensive spectroscopic anal. (HRMS, NMR) and chem. hydrolysis. The new dimer was formed via a [2 + 2] cycloaddition between two sym. tiliroside. Bioassay revealed that compound 1 showed significant α-glucosidase inhibitory activity with IC50 value at 4.40 μM. In the experiment, the researchers used rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1Quality Control of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol)
rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is oxidized in various tissues under either aerobic or anaerobic conditions through glycolysis; the oxidation reaction produces carbon dioxide, water, and ATP.Quality Control of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
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