Product Details of 27489-62-9In 2018 ,ãThe Rhodium Catalysed Direct Conversion of Phenols to Primary Cyclohexylaminesã?appeared in ChemCatChem. The author of the article were Tomkins, Patrick; Valgaeren, Carlot; Adriaensen, Koen; Cuypers, Thomas; Vos, Dirk E. De. The article conveys some information:
Cyclohexylamines are important intermediates in chem. industry, which are currently produced from petrochem. sources. Phenols, however, are an attractive sustainable feedstock. We here demonstrate the transformation of phenols with ammonia to primary cyclohexylamines. In contrast to previously reported chem. which used palladium catalysts, we here show that rhodium is an excellent catalyst for the formation of primary cyclohexylamines. Different parameters were studied and it was shown that the reaction is applicable to a scope of phenolic compounds providing high selectivity. In the experiment, the researchers used many compounds, for example, trans-4-Aminocyclohexanol(cas: 27489-62-9Product Details of 27489-62-9)
trans-4-Aminocyclohexanol(cas: 27489-62-9) belongs to anime. Nitrous acid converts secondary amines (aliphatic or aromatic) to N-nitroso compounds (nitrosamines): R2NH + HNO2 â?R2NâNO. Some nitrosamines are potent cancer-inducing substances, and their possible formation is a serious consideration when nitrites, which are salts of nitrous acid, are present in foods or pharmaceutical preparations. Tertiary amines give rise to nitrosamines more slowly; an alkyl group is eliminated as an aldehyde or ketone, along with nitrous oxide, N2O.Product Details of 27489-62-9
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