In 2022,Kim, Haeun; Jung, Yujin; Cho, Seung Hwan published an article in Organic Letters. The title of the article was ãDefluorinative C-C Bond-Forming Reaction of Trifluoromethyl Alkenes with gem-(Diborylalkyl)lithiumsã?COA of Formula: C13H26B2O4 The author mentioned the following in the article:
Authors report the transition-metal-free defluorinative C-C bond-forming reaction of trifluoromethyl alkenes with gem-(diborylalkyl)lithiums. This synthetic strategy provides access to a variety of 4,4-difluoro homoallylic diboronate esters, which serve as versatile intermediates in the efficient preparation of valuable gem-difluoroalkene derivatives Further synthetic modifications are conducted to demonstrate the synthetic utility of the obtained 4,4-difluoro homoallylic diboronate esters. In addition to this study using Bis[(pinacolato)boryl]methane, there are many other studies that have used Bis[(pinacolato)boryl]methane(cas: 78782-17-9COA of Formula: C13H26B2O4) was used in this study.
Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds.COA of Formula: C13H26B2O4 Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry. This stems from their ease of preparation combined with their ability to undergo a broad range of chemical transformations.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts