Application of 20880-92-6On March 11, 2022, Guo, Peng; Pang, Xiaobo; Wang, Ke; Su, Pei-Feng; Pan, Qiu-Quan; Han, Guan-Yu; Shen, Qian; Zhao, Zhen-Zhen; Zhang, Wenhua; Shu, Xing-Zhong published an article in Organic Letters. The article was ãNickel-Catalyzed Reductive Csp3-Ge Coupling of Alkyl Bromides with Chlorogermanesã? The article mentions the following:
Reductive cross-coupling provides facile access to organogermanes, but it remains largely unexplored. Herein the authors report a Ni-catalyzed reductive Csp3-Ge coupling of alkyl bromides with chlorogermanes. This work established a new method for producing alkylgermanes. The reaction proceeds under very mild conditions and tolerates various functionalities including ether, alc., alkene, nitrile, amine, ester, phosphonates, amides, ketone, and aldehyde. The application of this method to the modification of bioactive mols. is demonstrated. The experimental process involved the reaction of ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol(cas: 20880-92-6Application of 20880-92-6)
((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol(cas: 20880-92-6) is a useful reactant for examining the effectiveness of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-âII (CA-âII)â?Application of 20880-92-6 And it is used as chiral auxiliaries in Michael and Aldol addition reactions.
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