Related Products of 2240-88-2On October 8, 2021 ,ãSynthesis of N-(2-SF5-ethyl)amines and impact of the SF5 substituent on their basicity and lipophilicityã?was published in Tetrahedron. The article was written by Gilbert, Audrey; Langowski, Pauline; Paquin, Jean-Francois. The article contains the following contents:
The synthesis of N-(2-SF5-ethyl)amines e.g., I is reported via the SN2 reaction between various amines, e.g., Me (2S)-pyrrolidine-2-carboxylate and 2-(pentafluoro-λ6-sulfanyl)ethyl trifluoromethanesulfonate as the SF5-containing electrophile. A total of 14 examples of SF5-containing aliphatic amines were synthesized, with yields going from 19 to 92%. Moreover, the effect of the SF5 substituent on the basicity and the lipophilicity of the amine was evaluated, and the SF5 group showed to decrease both the pKaH and the log D (pH = 7.0) values.3,3,3-Trifluoropropan-1-ol(cas: 2240-88-2Related Products of 2240-88-2) was used in this study.
3,3,3-Trifluoropropan-1-ol(cas: 2240-88-2) is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.Related Products of 2240-88-2
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