Tamaki, Shota; Kitada, Nobuo; Kiyama, Masahiro; Fujii, Rika; Hirano, Takashi; Kim, Sung Bae; Maki, Shojiro published their research in Scientific Reports in 2021. The article was titled 《Color-tunable bioluminescence imaging portfolio for cell imaging》.SDS of cas: 78782-17-9 The article contains the following contents:
The present study describes a color-tunable imaging portfolio together with twelve novel coelenterazine (CTZ) analogs. The three groups of CTZ analogs create diverse hues of bioluminescence (BL) ranging from blue to far red with marine luciferases. We found that the hue completes the whole color palette in the visible region and shows red-shifted BL with a marine luciferase: for example, Renilla luciferase 8 (RLuc8) and Artificial Luciferase 16 (ALuc16) show 187 nm- and 105 nm-red shifted spectra, resp., by simply replacing the substrate CTZ with 1d. The optical properties of the new CTZ analogs were investigated such as the kinetic parameters, dose dependency, and luciferase specificity. The 2-series CTZ analogs interestingly have specificity to ALucs and are completely dark with RLuc derivatives, and 3d is highly specific to only NanoLuc. We further determined the theor. background of the red-shifted BL maximum wavelengths (λBL) values according to the extended π conjugation of the CTZ backbone using D. Functional Theory (DFT) calculations This color-tunable BL imaging system provides a useful multicolor imaging portfolio that efficiently images mol. events in mammalian cells. In the experiment, the researchers used many compounds, for example, Bis[(pinacolato)boryl]methane(cas: 78782-17-9SDS of cas: 78782-17-9)
Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds. Organoboron compounds are versatile intermediates and as such are some of the most important classes of reagents in modern organic chemistry. This stems from their ease of preparation combined with their ability to undergo a broad range of chemical transformations.SDS of cas: 78782-17-9
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts