ãExploring an anomaly: the synthesis of 7,7′-diazaindirubin through a 7-azaindoxyl intermediateã?was published in RSC Advances in 2020. These research results belong to Shriver, James A.; Wang, Katelyn R.; Patterson, Andrew C.; DeYoung, James R.; Lipsius, Richard J.. Safety of Oxetan-3-ol The article mentions the following:
Two independent methods generating 7-azaindoxyl as an intermediate verified that 7,7′-diazaindirubin was formed exclusively over 7,7′-diazaindigo. This contrasted with long-standing knowledge related to the reactivity of indoxyl, which proceeded via a radical-initiated homodimerization process, leading to indigo. A series of experiments confirmed 7-azaindoxyl as an intermediate with resulted suggesting a condensation pathway followed by oxidation In the experiment, the researchers used many compounds, for example, Oxetan-3-ol(cas: 7748-36-9Safety of Oxetan-3-ol)
Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Safety of Oxetan-3-ol
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