Name: (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diolOn September 25, 2006 ,《Zirconium Bis(Amido) Catalysts for Asymmetric Intramolecular Alkene Hydroamination》 was published in Organometallics. The article was written by Watson, Donald A.; Chiu, Melanie; Bergman, Robert G.. The article contains the following contents:
In situ combination of diphosphinic amides and Zr(NMe2)4 gave chiral Zr bis(amido) complexes. The complexes are competent catalysts for intramol. asym. alkene hydroamination, providing piperidines and pyrrolidines in up to 80% ee and high yield. This system uses an inexpensive precatalyst, readily prepared ligands and is the 1st asym. alkene hydroamination catalyst based upon a neutral Zr bis(amido) complex. In the experiment, the researchers used (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4Name: (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol)
(R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol(cas: 329735-68-4) belongs to phenols. Phenols are more acidic than typical alcohols.Name: (R)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12).
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