《Structure-function studies of the aminothiol radioprotectants. Effect of carbon chain length in mercaptoethylamine homologs》 was published in Radiation Research in 1971. These research results belong to Swartz, Harold M.; Copeland, Edmund S.; Richardson, Earl C.. COA of Formula: C5H14ClNS The article mentions the following:
A study of the relation between chemical structure of aminothiols such as β-mercaptoethylamine-HCl (I) and its propyl, butyl, pentyl, and hexyl homologs, and the phys. chem. radiation protection in Escherichia coli which were irradiated in the presence of 0.1M protectant at either 1°C or 77°K and equilibrated with 100% O2 or N2 prior to irradiation showed that in contrast to mammalian systems no abrupt reduction in radioprotection occurred when the carbon chain separating amino acids and thiol groups was lengthened from 3 to 4 or more units. Free radical studies which were observed by ESR spectroscopy of treated bacteria preparations irradiated at 77°K and bacteriolog. studies indicated a gradual decrease in efficiency with no change in the mechanism of action either in O2 or N2. These results suggest a protective effect of aminothiols by specific interactions with cell components in addition to acting via a more general, non-specific radical scavenging and (or) repair mechanism. The experimental process involved the reaction of 5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8COA of Formula: C5H14ClNS)
5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8) belongs to thiols. Thiols show many reactions like those of the hydroxyl compounds, such as formation of thioesters and thioethers (sulfides).COA of Formula: C5H14ClNS Toward oxidation, however, they differ profoundly from alcohols: whereas oxidation of an alcohol usually leads to a product in which the oxidation state of a carbon atom has been changed, oxidation of a thiol affects the sulfur atom.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts