《Ligand-promoted cobalt-catalyzed radical hydroamination of alkenes》 was published in Nature Communications in 2020. These research results belong to Shen, Xuzhong; Chen, Xu; Chen, Jieping; Sun, Yufeng; Cheng, Zhaoyang; Lu, Zhan. Synthetic Route of C6H12O The article mentions the following:
Here, a ligand-promoted cobalt-catalyzed Markovnikov-type selective radical hydroamination of alkenes with diazo compounds was reported. This operationally simple protocol uses unsym. NNN-tridentate (UNT) ligand, readily available alkenes and hydrosilanes to construct hydrazones I (R = C6H5, 4-FC6H4, 3-pyridyl, etc.; R1 = Et, t-Bu, 4-MeOC6H4) with good functional group tolerance. The hydrazones can underwent nitrogen-nitrogen bond cleavage smoothly to deliver valuable amine derivatives Addnl., asym. intermol. hydroamination of unactivated aliphatic terminal alkenes using chiral N-imidazolinylphenyl 8-aminoquinoline (IPAQ) ligands has also been achieved to afford chiral amine derivatives II (R = Et, 4-FC6H4, C6H5CH2CH2, etc.; PG = Boc, Bz, (CH2)2CH(Ph)2, etc.) with good enantioselectivities. In the experiment, the researchers used many compounds, for example, 5-Hexen-1-ol(cas: 821-41-0Synthetic Route of C6H12O)
5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Synthetic Route of C6H12O
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