《Synthesis and characterization of light-degradable bromocoumarin functionalized polycarbonates》 was written by Mueller, Ann-Kathrin; Jung, Dimitri; Sun, Jingjiang; Kuckling, Dirk. Name: 2-Aminopropane-1,3-diol And the article was included in Polymer Chemistry in 2020. The article conveys some information:
Biocompatible polymeric materials that can degrade in response to external irradiation with high spatial and temporal control show enormous potential in the field of biomedical applications. Herein, two six-membered cyclic carbonate monomers with a light-cleavable bromocoumarin functional pendent moiety attached via a carbamate linkage were prepared from 2-amino-1,3-propanediol (serinol) and 2-(aminomethyl)-2-methylpropane-1,3-diol, resp. A series of light-degradable polycarbonates were synthesized by organo-catalyzed ring opening polymerization (ROP) of both monomers, and meanwhile their polymerization kinetics were investigated. Upon light-induced deprotection, both types of polycarbonates degraded rapidly into low mol.-weight compounds The results of size exclusion chromatog. (SEC), NMR (NMR) spectroscopy and UV/visible (UV/VIS) spectroscopy confirmed the polymer structures and the light-induced degradation behavior. The photo-cleavage rates of bromocoumarin pendent groups and the degradation rates of the polymers were strongly dependent on polymer structures and used solvents. In the experimental materials used by the author, we found 2-Aminopropane-1,3-diol(cas: 534-03-2Name: 2-Aminopropane-1,3-diol)
2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Nitrous acid converts secondary amines (aliphatic or aromatic) to N-nitroso compounds (nitrosamines): R2NH + HNO2 → R2N―NO. Some nitrosamines are potent cancer-inducing substances, and their possible formation is a serious consideration when nitrites, which are salts of nitrous acid, are present in foods or pharmaceutical preparations. Tertiary amines give rise to nitrosamines more slowly; an alkyl group is eliminated as an aldehyde or ketone, along with nitrous oxide, N2O.Name: 2-Aminopropane-1,3-diol
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