Application of 873-75-6In 2019 ,《Iridium-Catalyzed Alkylation of Amine and Nitrobenzene with Alcohol to Tertiary Amine under Base- and Solvent-Free Conditions》 was published in Journal of Organic Chemistry. The article was written by Li, Chao; Wan, Ke-feng; Guo, Fu-ya; Wu, Qian-hui; Yuan, Mao-lin; Li, Rui-xiang; Fu, Hai-yan; Zheng, Xue-li; Chen, Hua. The article contains the following contents:
Herein, an efficient and green method for the selective synthesis of tertiary amines has been developed that involves iridium-catalyzed alkylation of various primary amines with aromatic or aliphatic alcs. Notably, the catalytic protocol enables this transformation in the absence of addnl. base and solvent. Furthermore, the alkylation of nitrobenzene with primary alc. to tertiary amine has also been achieved by the same catalytic system. Deuterium-labeling experiments and a series of control experiments were conducted, and the results suggested that an intermol. borrowing hydrogen pathway might exist in the alkylation process. The results came from multiple reactions, including the reaction of (4-Bromophenyl)methanol(cas: 873-75-6Application of 873-75-6)
(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Application of 873-75-6 It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.
Referemce:
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