《A new catalytic approach for aerobic oxidation of primary alcohols based on a Copper(I)-thiophene carbaldimines》 was written by Lagerspets, Emi; Valbonetti, Evelyn; Eronen, Aleksi; Repo, Timo. Application of 1195-59-1This research focused onthiophenyl methanimine preparation; primary alc copper thiophenyl methanimine catalyst oxidation; diol copper thiophenyl methanimine catalyst oxidation. The article conveys some information:
Novel Cu(I) thiophene carbaldimine catalysts for the selective aerobic oxidation of primary alcs. to their corresponding aldehydes and various diols to lactones or lactols was reported. In the presence of the in-situ generated Cu(I) species, a persistent radical (2,2,6,6-tetramethylpiperdine-N-oxyl (TEMPO)) and N-methylimidazole (NMI) as an auxiliary ligand, the reaction proceeds under aerobic conditions and at ambient temperature Especially the catalytic system of 1-(thiophen-2-yl)-N-(4-(trifluoromethoxy)phenyl)methanimine with copper(I)-iodide showed high reactivity for all kind of alcs. (benzylic, allylic and aliphatic). In the case of benzyl alc. even 2.5 mol% of copper loading gave quant. yield. Beside high activity under aerobic conditions, the catalysts ability to oxidize 1,5-pentadiol to the corresponding lactol (86% in 4 h) and N-phenyldiethanolamine to the corresponding morpholine derivate lactol (86% in 24 h) is particularly noteworthy. In the experimental materials used by the author, we found 2,6-Pyridinedimethanol(cas: 1195-59-1Application of 1195-59-1)
2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Application of 1195-59-1
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts