Fishbein, Lawrence; Cavanaugh, M. A. published an article in 1965, the title of the article was Detection and paper chromatography of N-substituted hydroxy, 2-hydroxyethyl, 2-chloroethyl, and N,N-bis(2-hydroxyethyl) derivatives.Product Details of 2160-93-2 And the article contains the following content:
Studies of the metabolism, degradation, and mutagenicity of N-substituted 2-hydroxyethyl, and 2-chloroethyl pesticides, N-hydroxy carbamates and related N and C substituted OH derivatives prompted the need to evaluate various categories of detecting reagents as to their possible utility for subsequent differentiation, and identification of the above moieties in a variety of aliphatic, aromatic, and cyclic compounds One-dimensional descending chromatography was carried out on Whatman Number 1 filter paper by using the following solvent systems: BuOH-HOAc-H2O (5:1:4); BuOH-EtOH-H2O (7:1:2); and iso-PrOH-NH4OH-H2O (80:5:15). Detecting reagents were: (1) 5% Na nitroprusside-10% MeCHO mixed with an equal volume of 2% aqueous Na2CO3; (2) FCNP reagent (mixture of equal volumes of 10% NaOH, 10% Na nitroprusside, and 10% K ferricyanide diluted with 3 volumes of H2O, and mixed with an equal volume of Me2CO); (3) 0.2% ninhydrin in Me2CO; (4) 0.2% ninhydrin in Me2CO with 5% C5H5N; (5) 1% FeCl3 in MeOH; (6) 10% p-dimethylaminobenzaldehyde in 1:4 Me2CO-concentrated HCl; (7) 2 ml. trans-cinnamaldehyde in 95 ml. EtOH, 18.5 ml. H2O, and 6 ml. concentrated HCl; (8) 5% 4-(p-nitrobenzyl)pyridine in Me2CO; (9) 0.5% barbituric acid in EtOH containing 2 ml. 85% H3P4O (10) equal volumes of C5H5N and MeCHO; (11) 1% isatin in iso-PrOH containing 1% C5H5N and 1.5% Zn(OAc)2; (12) 0.5% Cu(OAc)2 in EtOH containing 0.1% Me2NH and 2% (HOC2H4)3N; (13) 0.5 % 2,6-dibromo-N-chloro-p-quinone imine in 4:1 dioxane-Me2CO; (14) 5% N,2,6-trichlorobenzoquinone imine in 4:1 dioxane-Me2CO; (15) 3% K nitrosodisulfonate in N NaOH; (16) 1% KMnO4. The Rf values and color of spots with the reagents are given for 76 N and C substituted N-hydroxy, 2-hydroxyethyl, 2-chloroethyl, and N,N-bis(2-hydroxyethyl) derivatives and related compounds The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Product Details of 2160-93-2
2,2′-(tert-Butylazanediyl)diethanol(cas:2160-93-2) belongs to alcohols. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Product Details of 2160-93-2
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts