The author of 《General and Phosphine-Free Cobalt-Catalyzed Hydrogenation of Esters to Alcohols》 were Shao, Zhihui; Zhong, Rui; Ferraccioli, Raffaella; Li, Yibiao; Liu, Qiang. And the article was published in Chinese Journal of Chemistry in 2019. Application In Synthesis of 3-Pyridinemethanol The author mentioned the following in the article:
The first non-noble metal catalytic system that enabled an efficient hydrogenation of non-activated esters to alcs. in the absence of phosphine ligands (with a maximum turnover number of 2391) was described. The general applicability of this protocol was demonstrated by the high-yielding hydrogenation of 39 ester substrates including aromatic/aliphatic esters, lactones, polyesters and various pharmaceutical mols. In the experimental materials used by the author, we found 3-Pyridinemethanol(cas: 100-55-0Application In Synthesis of 3-Pyridinemethanol)
3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Application In Synthesis of 3-Pyridinemethanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts