The author of 《1,2-Amino alcohol-dependent Petasis allylboration for racemic and chiral homoallylamines》 were Lin, Zi-Wei; Zhou, Yang; Zhao, Zhen-Ni; Zhao, Yan; Liu, Jun; Huang, Yi-Yong. And the article was published in Organic Chemistry Frontiers in 2019. Application In Synthesis of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol The author mentioned the following in the article:
Petasis allylboration among an aldehyde RCHO (R = hexyl, cyclohexyl, Ph, 6-methoxy-3-pyridinyl, etc.), 1,2-amino alcs. such as (2S)-2-amino-3-phenylpropan-1-ol, (2S)-2-amino-2-phenylethan-1-ol, (1S,2R)-1-amino-2,3-dihydro-1H-inden-2-ol, etc. and pinacolallylboronate has been successfully accomplished at room temperature without any catalysts. A proposed reaction pathway involving the allylboration of an in situ-generated imine through a six-membered chairlike transition state is suggested to understand the role of a positioned hydroxy group and the diastereoselective outcome I. The experimental part of the paper was very detailed, including the reaction process of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Application In Synthesis of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol)
(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Application In Synthesis of (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts