In 2022,Lin, Shizhuo; Sheng, Xing; Zhang, Xiangyu; Liu, Haibo; Luo, Chujun; Hou, Shuaishuai; Li, Bin; Chen, Xiuwen; Li, Yibiao; Xie, Feng published an article in Journal of Organic Chemistry. The title of the article was 《Layered Double Hydroxides as Reusable Catalysts for Cyclocondensation of Amidines and Aminoalcohols: Access to Multi-functionalized Oxazolines》.Name: 2-Aminopropane-1,3-diol The author mentioned the following in the article:
An efficient catalytic protocol based on reusable MgAl-layered double hydroxides has been developed for the synthesis of multi-functionalized oxazolines via the cyclocondensation of amidines and aminoalcs. The developed method has a broad substrate scope and excellent functional group tolerance and uses a reusable catalyst. The catalyst can be conveniently recycled by filtration and reused for at least five times without obvious deactivation. Addnl., the selective ortho C-H silylation of oxazolines was performed using Ru(II) as the catalyst and tri-Et silane as the silylating reagent, which proved to be a convenient and practical method for the synthesis of versatile organosilyl-functionalized oxazolines with advantageous biol. and phys. properties. In the part of experimental materials, we found many familiar compounds, such as 2-Aminopropane-1,3-diol(cas: 534-03-2Name: 2-Aminopropane-1,3-diol)
2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Amine, any member of a family of nitrogen-containing organic compounds that is derived, either in principle or in practice, from ammonia (NH3). Naturally occurring amines include the alkaloids, which are present in certain plants; the catecholamine neurotransmitters (i.e., dopamine, epinephrine, and norepinephrine); and a local chemical mediator, histamine, that occurs in most animal tissues.Name: 2-Aminopropane-1,3-diol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts