《Structure Revision of Protoaculeine B, a Post-translationally Modified N-Terminal Residue in the Peptide Toxin Aculeine B》 was written by Irie, Raku; Miyako, Kei; Matsunaga, Satoko; Sakai, Ryuichi; Oikawa, Masato. Computed Properties of C8H19NO2 And the article was included in Journal of Natural Products on April 23 ,2021. The article conveys some information:
The structure of protoaculeine B, the N-terminal residue of the marine peptide toxin aculeine B, is revised to the cis-1,3-disubstituted tetrahydro-β-carboline framework. We prepared two truncated model compounds that lack a long-chain polyamine using the one-step Pictet-Spengler reaction of tryptophan and compared their NMR, mass spectra, and chem. reactivity with those of the natural protoaculeine B. The synthetic models reproduced the profiles of the natural product well, which confirmed the appropriateness of the structure revision. After reading the article, we found that the author used 4,4-Diethoxybutan-1-amine(cas: 6346-09-4Computed Properties of C8H19NO2)
4,4-Diethoxybutan-1-amine(cas: 6346-09-4) belongs to anime. Reduction of nitro compounds, RNO2, by hydrogen or other reducing agents produces primary amines cleanly (i.e., without a mixture of products), but the method is mostly used for aromatic amines because of the limited availability of aliphatic nitro compounds. Reduction of nitriles and oximes (R2C=NOH) also yields primary amines.Computed Properties of C8H19NO2
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