《Iridium-Catalyzed Alkylation of Secondary Alcohols with Primary Alcohols: A Route to Access Branched Ketones and Alcohols》 was published in Journal of Organic Chemistry in 2020. These research results belong to Genc, Sertac; Gulcemal, Suleyman; Gunnaz, Salih; Cetinkaya, Bekir; Gulcemal, Derya. Reference of (4-Bromophenyl)methanol The article mentions the following:
Under borrowing hydrogen conditions, NHC-iridium(I) catalyzed the direct or one-pot sequential synthesis of α,α-disubstituted ketones RCOCH(CH2R1)CH2R2 [R = Ph, 2-naphthyl, 4-MeOC6H4, etc.; R1 = Ph, 1-naphthyl, n-heptyl, etc.; R2 = Ph, 1-naphthyl, 4-MeOC6H4, etc.] via the alkylation of secondary alcs. with primary alcs. was reported. Notably, the present approach provides a new method for the facile synthesis of α,α-disubstituted ketones and featured with several characteristics, including a broad substrate scope, using easy-to-handle alcs. as starting materials, and performing the reactions under aerobic conditions. Moreover, the selective one-pot formation of β,β-disubstituted alcs. PhCH(OH)CH(CH2R3)CH2R4 [R3 = Ph, n-heptyl; R4 = Ph, 4-MeC6H4, 4-BrC6H4] was achieved by the addition of an external hydrogen source to the reaction mixture In addition to this study using (4-Bromophenyl)methanol, there are many other studies that have used (4-Bromophenyl)methanol(cas: 873-75-6Reference of (4-Bromophenyl)methanol) was used in this study.
(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Reference of (4-Bromophenyl)methanol It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts