《Synthesis, characterization, and antimicrobial evaluation of random poly(ester-carbonate)s bearing pendant primary amine in the main chain》 was written by Dong, Peng; Feng, Jing; Li, Sujuan; Sun, Tingli; Shi, Qingshan; Xie, Xiaobao. HPLC of Formula: 534-03-2 And the article was included in Polymers (Basel, Switzerland) in 2020. The article conveys some information:
Starting from primary amine bearing cyclic carbonate tert-butyl-(2-oxo-1,3-dioxan-5-yl) carbamate (TBODC) and caprolactone (CL), amphiphilic poly(caprolactone-ran-amino tri-Me carbonate)s (P(CL-ran-ATC)s) random copolymers with controlled mol. weight and composition were synthesized via ring opening polymerization (ROP) and deprotection, using stannous octoate (Sn(Oct)2) as catalyst and benzyl alc. (BnOH) as initiator. Therefore, hydrophilic/lipophilic ratio (HLR) of the P(CL-ran-ATC)s copolymers can be finely adjusted by the feed ratio of TBODC and CL. The antimicrobial activity against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) of P(CL-ran-ATC)s were proportional to HLR, and P(CL-ran-ATC)s presented more vigorous bactericidal activity towards S. aureus. The min. inhibitory concentration (MIC) values of P(CL-ran-ATC 50.9%) are 2000μg mL-1 and 3000μg mL-1 for S. aureus and E. coli. While P(CL-ran-ATC 50.9%) exhibited deficient hemolytic activity as 1.41%. In addition, the P(CL-ran-ATC)s showed extremely low cytotoxicity towards fibroblast L929 cells. After reading the article, we found that the author used 2-Aminopropane-1,3-diol(cas: 534-03-2HPLC of Formula: 534-03-2)
2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Left-handed and right-handed forms (mirror-image configurations, known as optical isomers or enantiomers) are possible when all the substituents on the central nitrogen atom are different (i.e., the nitrogen is chiral). With amines, there is extremely rapid inversion in which the two configurations are interconverted.HPLC of Formula: 534-03-2
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