In 2019,New Journal of Chemistry included an article by Ahamad, M. Naqi; Shahid, M.; Ansari, Azaj; Kumar, Manjeet; Khan, Ishaat M.; Ahmad, Musheer; Rahisuddin; Arif, Rizwan. Quality Control of 3-Aminopropan-1-ol. The article was titled 《A combined experimental and theoretical approach to investigate the structure, magnetic properties and DNA binding affinity of a homodinuclear Cu(II) complex》. The information in the text is summarized as follows:
Herein, an antiferromagnetic homodinuclear Cu(II) complex of propanolamine, [Cu2(pa)2(OAc)2] (1), containing an acetate auxiliary was crystallized out. The complex was characterized by spectral, x-ray crystallog., magnetic and DFT/TD-DFT studies. Single crystal x-ray data reveal that 1 crystallizes in the triclinic system with the P1̅ space group, and each Cu(II) ion adopts a four-coordinated square planar geometry with the [N,O,O,O] donor set. The two [Cu(CH3COO)(pa)]+ units are connected through two alkoxy groups of the pa- ligand belonging to each unit; this gave a binuclear Cu(II) system with the bridging Cu1-O1-Cu2 angle = 103.81° and the intradimer Cu···Cu distance = 3.022 Å. The exptl. results obtained via the binding experiments of the present complex with DNA are in line with the theor. results. The auxiliary acetate group and the bridged pa- ligand facilitate the binding tendency of the complex to DNA in the minor groove region (as confirmed by docking anal.), thereby forming stronger H-bonding interactions. The easy transfer of an electron from the HOMO of DNA to the LUMO of the complex further supports the existence of a stronger binding interaction, as confirmed by the DFT anal. Temperature variable magnetic studies (SQUID measurements) revealed strong antiferromagnetic interactions (J = -222.4(2) cm-1) between two Cu(II) nuclei in a mol., and the presence of these interactions was further supported by theor. studies. The larger Cu···Cu distance and Cu-O-Cu angle are the factors behind the antiferromagnetic exchange between two Cu(II) centers. Thus, the present study establishes that the fine tuning of structures in transition metal complexes can gave magnetically and biol. important mols. for future applications. In the experiment, the researchers used many compounds, for example, 3-Aminopropan-1-ol(cas: 156-87-6Quality Control of 3-Aminopropan-1-ol)
3-Aminopropan-1-ol(cas: 156-87-6) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).Quality Control of 3-Aminopropan-1-ol
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