On May 31, 2022, Tsai, Yu-Hsuan; Tsai, Chia-Wei; Tipple, Christopher A. published an article.Application In Synthesis of SweetPearlR P300 DC Maltitol The title of the article was A validated method for the analysis of sugars and sugar alcohols related to explosives via liquid chromatography mass spectrometry (LC-MS) with post-column addition. And the article contained the following:
The anal. of eleven sugars and sugar alcs. was performed via liquid chromatog. with mass spectrometric detection. A method for the separation of the sugars and sugar alcs., with the specific emphasis on the separation of the isomeric pair sorbitol/mannitol, was developed. The method was validated, with the following studies included: limit of detection, stability, interference, and ionization suppression. The limits of detection ranged from 9.2×10-3 mM for maltitol up to 2.3 mM for erythrose (3.2 ppm up to 2.8 x102 ppm). The sugars and sugar alcs. were tested at low and high concentrations over 5 days for their stability. Most of the sugars were stable for at least two days at the high concentration, while 6 were stable at the low concentration indicating the need to analyze promptly. An interference study was conducted with nitrated sugars present, which may be present in the forensic application for which the method is intended. There was no interference observed from either mannitol hexanitrate (MHN) or erythritol tetranitrate (ETN). Finally, the effect of a sample collection matrix was evaluated for its potential to either suppress or enhance the anal. signal from the sugars and sugar alcs. There was no significant enhancement/suppression observed, at high or low concentration, for any analyte except fructose. A field trial was made of forensic samples which demonstrated the potential of the procedure. The method was successfully used for the anal. of six post-blast samples, which indicated the presence of at least one sugar/sugar alc. in five of those samples. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Application In Synthesis of SweetPearlR P300 DC Maltitol
The Article related to forensic sugar alc liquid chromatog mass spectrometry validation, Biochemical Methods: Chromatographic and other aspects.Application In Synthesis of SweetPearlR P300 DC Maltitol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts