On June 15, 2007, Juhasz, Laszlo; Docsa, Tibor; Brunyaszki, Attila; Gergely, Pal; Antus, Sandor published an article.Electric Literature of 280752-78-5 The title of the article was Synthesis and glycogen phosphorylase inhibitor activity of 2,3-dihydrobenzo[1,4]dioxin derivatives. And the article contained the following:
Novel 5-benzyl and 5-benzylidene-thiazolidine-2,4-diones carrying 2,3-dihydrobenzo[1,4]dioxin pharmacophore were synthesized and their glycogen phosphorylase inhibitor activity was also studied. Compound I possesses a high glycogen phosphorylase inhibitory activity with a Ki = 10-12 μM. The experimental process involved the reaction of (6-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol(cas: 280752-78-5).Electric Literature of 280752-78-5
The Article related to glycogen phosphorylase inhibitor antidiabetic dihydrobenzodioxin thiazolidinedione preparation sar, Pharmacology: Structure-Activity and other aspects.Electric Literature of 280752-78-5
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