Guo, Wusheng; Laserna, Victor; Rintjema, Jeroen; Kleij, Arjan W. published an article in 2016, the title of the article was Catalytic One-Pot Oxetane to Carbamate Conversions: Formal Synthesis of Drug Relevant Molecules.SDS of cas: 78-26-2 And the article contains the following content:
Oxetanes are versatile building blocks in drug-related synthesis to induce property-modulating effects. Whereas related oxiranes are widely used in coupling chem. with CO2 to afford value-added commodity chems., oxetane/CO2 couplings remain extremely limited despite the recent advances in the synthesis of these four-membered heterocycles. Here we report an effective one-pot three-component reaction (3CR) strategy for the coupling of (substituted) oxetanes, amines, and CO2 to afford a variety of functionalized carbamates with excellent chemoselectivity and good yields. The process is mediated by an aluminum-based catalyst under relatively mild conditions and the developed catalytic methodol. can be applied to the formal synthesis of two pharmaceutically relevant carbamates with the 3CR being a key step. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).SDS of cas: 78-26-2
The Article related to carbamate preparation, three component reaction carbon dioxide oxetane amine aluminum catalyst, General Organic Chemistry: Synthetic Methods and other aspects.SDS of cas: 78-26-2
Referemce:
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Alcohols – Chemistry LibreTexts