Cabani, S.; Mollica, V.; Lepori, L.; Lobo, S. T. published an article in 1977, the title of the article was Volume changes in the proton ionization of amines in water. 2. Amino alcohols, amino ethers, and diamines.Formula: C3H10ClNO And the article contains the following content:
From d. measurements (25°) of aqueous solutions at various concentrations of solute, apparent molar volumes of some open-chain bifunctional primary, secondary and tertiary amines were determined; the compounds studied were X(CH2)nNH2 (X = HO, MeO, H2N; n = 2,3) and 2-XCH2CH2OH (X = MeNH, EtNH, Me2N, Et2N) and their mono- and dihydrochlorides, for which ΔV1° and ΔV2° for the 1st and 2nd steps of proton ionization were calculated from the limiting partial molar volumes Values ΔV1° for the above bifunctional amines are compared with the corresponding values for monofunctional amines, and the difference in ΔV1° caused by the introduction of the 2nd hydrophilic center is discussed. The volumes and entropies of ionization of the amines and carboxylic acids are compared, and the deviations of these functions from predictions based on simple electrostatic theories are considered. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Formula: C3H10ClNO
The Article related to amine ionization molar volume, Physical Organic Chemistry: Structure Effects and other aspects.Formula: C3H10ClNO
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