Bae, Sung Jin et al. published their patent in 2012 |CAS: 386704-04-7

The Article related to cyclohexane preparation nitric oxide production inhibitor treatment pain, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Application of 386704-04-7

On April 5, 2012, Bae, Sung Jin; Yi, Han Ju; Hwang, Sun Gwan; Jeong, Mo Ses; Yoon, Yeo Jin; Chae, Sang Mi; Park, Joo Young; Ryu, Eun Ju published a patent.Application of 386704-04-7 The title of the patent was Cyclohexane derivatives as NO production inhibitors and their preparation and use for the treatment of pain. And the patent contained the following:

The invention relates to cyclohexane derivatives of formula I, which are inhibitors of nitric oxide production and which are useful in the treatment of pain. Compounds of formula I wherein Ar is (un)substituted Ph, (un)substituted pyridine and (un)substituted pyridine N-oxide; X is O, C(O)O, NH, etc.; Y is CH2, O and NH and derivatives; A is O and NH; Q is CH and N; m is 0 to 2; n is 0 and 1; and pharmaceutically acceptable salts, isomers, solvates and hydrates thereof, are claimed. Example compound II was prepared by a general procedure (procedure given). All the invention compounds were evaluated for their NO production inhibitory activity. From the assay, it was determined that compound II exhibited IC50 values in the range 7.5 – 9.9 μM. The experimental process involved the reaction of (6-(Trifluoromethyl)pyridin-3-yl)methanol(cas: 386704-04-7).Application of 386704-04-7

The Article related to cyclohexane preparation nitric oxide production inhibitor treatment pain, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Application of 386704-04-7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts