On June 30, 2021, Al-Tamimi, Jameel; Ebaid, Hossam; Hassan, Iftekhar; Alhazza, Ibrahim M.; Hailan, Waleed; Al-Khalifa, Mohammed published an article.Product Details of 96-76-4 The title of the article was Samsum ant venom protects against carbon tetrachloride-induced acute spleen toxicity in vivo. And the article contained the following:
Many active mols. used in the development of new drugs are produced by ants. Present study assessed antioxidant and anti-inflammatory properties of Samsum ant venom (SAV) extract in carbon tetrachloride (CCL4)-induced spleen toxicity. Toxicity and oxidative stress were measured in four exptl. groups: a neg. control group without any treatment, a pos. control group (CCl4-treated rats; a single dose of 1 mL/kg CCL4), an exptl. group of CCl4-treated rats co-treated daily with SAV (100 μl), and a group to determine safe use with rats treated only with SAV (100 μl) daily for 3 wk. CCl4-treatment led to an elevation in toxicity and oxidative stress. CCl4 significantly elevated malondialdehyde (MDA) levels, as well as expression of inhibitor of κB (IκB) and tumor necrosis factor-α (TNF-α) proteins. On the other hand, a decrease in glutathione (GSH) and catalase (CAT) levels were detected in CCl4-treated rats. Co-treatment with SAV was found to reduce these inflammatory and oxidative parameters. SAV elucidated a significant recovery of MDA concentration as well as a significant restoration in GSH levels compared to CCl4-treated rats; however, SAV increased CAT levels compared to normal rats. Hence, SAV was found to restore splenomegaly induced in CCl4-treated rats. Histopathol. anal. also favored the biochem. anal. showing improvement in splenic architecture in CCl4 and SAV co-treated rats. The antioxidant properties of SAV may potentially enhance anti-inflammatory actions and improve spleen structure and function in CCl4-challenged rats. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Product Details of 96-76-4
The Article related to pachycondyla venom antioxidant antiinflammatory carbon tetrachloride acute spleen toxicity, ccl4, inflammatory markers, oxidative stress, samsum ant venom, Placeholder for records without volume info and other aspects.Product Details of 96-76-4
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts