On April 30, 1978, Perchonock, Carl D.; Loev, Bernard published an article.Synthetic Route of 42900-89-0 The title of the article was Synthesis of some aromatic prostaglandin analogs. And the article contained the following:
Some aromatic prostaglandin analogs, with a benzene (I) (R = H, Me) or a dimethoxybenzene ring (II) in place of the cyclopentane moiety, were synthesized. The key intermediates in the syntheses were lactols III and IV, which were elaborated to the final products via two olefination reactions. I (R = H) was twice as potent as phenylbutazone and nine times as potent as aspirin in inhibiting prostaglandin synthetase activity. The experimental process involved the reaction of Isochroman-3-ol(cas: 42900-89-0).Synthetic Route of 42900-89-0
The Article related to aromatic prostaglandin analog, benzene prostaglandin analog, Alicyclic Compounds: Cyclopentanes, Including Fulvenes and Fulvalenes and other aspects.Synthetic Route of 42900-89-0
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