Kim, Eun-Hee et al. published their research in Natural Product Communications in 2021 |CAS: 585-88-6

The Article related to antimicrobial antiinflammatory effect polygonum cuspidatum ethanol extract mouthwash component, Pharmacology: Effects Of Antimicrobials and Parasiticides and other aspects.HPLC of Formula: 585-88-6

On April 30, 2021, Kim, Eun-Hee; Kim, Jin-Cheon; Kim, Hye Kyung; Jang, Young-Ah published an article.HPLC of Formula: 585-88-6 The title of the article was Antimicrobial and Anti-Inflammatory Effects of the Ethanol Extract of Polygonum cuspidatum as a Mouthwash Component. And the article contained the following:

Polygonum cuspidatum (PC) has been used as traditional Korean medicine to treat various diseases including asthma, hypertension, cancer, and arteriosclerosis. In this study, we assessed the antibacterial and anti-inflammatory effects of PC ethanol extract Persistent antibacterial activity against Streptococcus mutans for up to 23 days was observed when the extract was used at a concentration of 10 mg/mL. The min. inhibitory concentration of PC against S. mutans was 0.2 mg/mL and the min. bactericidal concentration was 10 mg/mL. We compared the antimicrobial activities of S. mutagens cultured with or without PC. Bacterial activity was observed only in the group where RE was not added. The anti-inflammatory effect of PC on RAW264.7 cells was assessed using the MTT assay; changes in nitric oxide (NO) production and inflammatory cytokine levels (tumor necrosis factor [TNF]-α and interleukin [IL]-6) were measured in the presence of PC. In lipopolysaccharide-induced RAW264.7 cells, PC inhibited NO production by 68.6% when used at a concentration of 50μg/mL. The expression of TNF-α and IL-6 was reduced by PC in a concentration-dependent manner. These results suggest that the ethanol extract of PC could be used as a mouthwash component with antibacterial and anti-inflammatory effects. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).HPLC of Formula: 585-88-6

The Article related to antimicrobial antiinflammatory effect polygonum cuspidatum ethanol extract mouthwash component, Pharmacology: Effects Of Antimicrobials and Parasiticides and other aspects.HPLC of Formula: 585-88-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts