On October 16, 2006, Kato, Keisuke; Matsuba, Chie; Kusakabe, Taichi; Takayama, Hiroyuki; Yamamura, Shigeo; Mochida, Tomoyuki; Akita, Hiroyuki; Peganova, Tat’yana A.; Vologdin, Nikolai V.; Gusev, Oleg V. published an article.Category: alcohols-buliding-blocks The title of the article was 2,2′-Isopropylidenebis[(4S,5R)-4,5-di(2-naphthyl)-2-oxazoline] ligand for asymmetric cyclization-carbonylation of meso-2-alkyl-2-propargylcyclohexane-1,3-diols. And the article contained the following:
The oxidative cyclization-carbonylation of meso-2-alkyl-2-propargylcyclohexane-1,3-diols I (R = Me, n-Pr, H2C:CHCH2) mediated by Pd(II) with chiral bisoxazoline (box ligand) afforded bicyclic β-alkoxyacrylates II. Based on a ligand screening, 2,2′-isopropylidenebis[(4S,5R)-4,5-di(2-naphthyl)-2-oxazoline] ligand has been developed. The products II with a chiral quaternary carbon were obtained in 71-100% yields with 85-95% ee. The experimental process involved the reaction of (R)-2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol(cas: 306281-86-7).Category: alcohols-buliding-blocks
The Article related to benzofuran perhydro carboxymethylene asym synthesis, cyclohexanediol propargyl preparation enantioselective cyclization carbonylation oxazoline palladium catalyst, Heterocyclic Compounds (One Hetero Atom): Areno- and Diarenofurans and other aspects.Category: alcohols-buliding-blocks
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts