On September 30, 2000, Hirose, Keiji; Ogasahara, Kazuko; Nishioka, Kazuyuki; Tobe, Yoshito; Naemura, Koichiro published an article.Name: (R)-2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol The title of the article was Enantioselective complexation of phenolic crown ethers with chiral aminoethanol derivatives: effects of substituents of aromatic rings of hosts and guests on complexation. And the article contained the following:
Optically active azophenolic crown ethers having Ph groups substituted at the resp. para-position were prepared and their association constants with chiral aminoethanol derivatives, including 2-amino-2-phenylethanols having an electron-donating or an electron-withdrawing group, were determined in chloroform by means of UV-vis titration methods. The enantioselectivities of these crown ethers are estimated from the ratio of the association constants KR/KS and the effect of aromatic substituents of both hosts and guests on the binding abilities and enantioselectivities is discussed. The structures of the complexes were investigated on the basis of the 1H NMR and UV-vis spectra. The experimental process involved the reaction of (R)-2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol(cas: 306281-86-7).Name: (R)-2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol
The Article related to enantioselective complexation phenolic crown ether chiral aminoethanol substituent effect, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.Name: (R)-2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol
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