On August 1, 2021, Hauk, Armin; Pahl, Ina; Dorey, Samuel; Menzel, Roberto published an article.Computed Properties of 96-76-4 The title of the article was Using extractables data from single-use components for extrapolation to process equipment-related leachables: The toolbox and justifications. And the article contained the following:
Quant. information on process equipment-related leachables (PERLs) is required for process qualification and within a safety assessment. Extractables data for single-use equipment are suitable and applicable if the extractables study conditions fit or are bracketing the expected conditions of use. It is necessary to extrapolate extractables data when the expected in-use conditions are not covered by the test conditions. Methods for such quant. extrapolation of extractables data toward potential PERLs are therefore needed. They are comprehensively described in this publication and include: scaling of extractables data for devices of different sizes adjusted to process-volumes, extrapolation to temperatures different from the extraction temperature, extrapolations to different solvent compositions, extrapolation to various contact times, and the combination of extractables data from individual components to assess assemblies. These extrapolation methods yield extractables data as if an extractables study had been performed. The methods presented are consistently derived from basic physicochem. principles. The relevant, underlying phys. parameters are obtained from extractables experiments and are compared with published data. The applicability and justification of the proposed calculation methods are discussed and benchmarked against exptl. findings. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Computed Properties of 96-76-4
The Article related to hexadecane dodecane film temperature phase equilibrium algorithm, Biochemical Methods: Other (Not Covered At Other Subsections) and other aspects.Computed Properties of 96-76-4
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