Ferrari, G. et al. published their research in Arzneimittel-Forschung in 1979 |CAS: 62640-03-3

The Article related to phosphorylated creatinol, Aliphatic Compounds: Alcohol and Thiol Esters With Inorganic Acids and other aspects.Category: alcohols-buliding-blocks

On October 31, 1979, Ferrari, G.; Casagrande, C. published an article.Category: alcohols-buliding-blocks The title of the article was Synthesis and chemical properties of N- and O-phosphorylated derivatives of creatinol. And the article contained the following:

Treatment of HOCH2CH2NMeC(:NH)NH2.HBr (I.HBr) with POCl3 gave, after hydrolysis, HOCH2CH2NMeC(:NH)NHP(O)(OH)2 (II), from which the di-Na, Ca and Ba salts were prepared II was also prepared by treating I.HBr with H3PO4 and heating the resultant I.H3PO4 to 165° under 5 min pressure. Treatment of Na+ [(4-O2NC6H4CH2O)2P(O)NCN]- with MeNHCH2CH2OH.HCl followed by hydrogenolysis gave HOCH2CH2NMeC(:NH)NHP(O)(OH)2, which rearranged to II upon heating at 155° for 1 h. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Category: alcohols-buliding-blocks

The Article related to phosphorylated creatinol, Aliphatic Compounds: Alcohol and Thiol Esters With Inorganic Acids and other aspects.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts