On April 17, 2015, Liu, Yan-Kai; Li, Zhi-Long; Li, Ji-Yao; Feng, Huan-Xi; Tong, Zhi-Ping published an article.Quality Control of Isochroman-3-ol The title of the article was Open-Close: An Alternative Strategy to α-Functionalization of Lactone via Enamine Catalysis in One Pot under Mild Conditions. And the article contained the following:
An open-close strategy in asym. catalysis is newly developed. With this powerful strategy, lactols are directly applied as potential precursors of lactones in enamine-based asym. Michael reactions providing a facile access to α-functionalized lactones containing two adjacent stereogenic centers as a single diastereomer, e.g. I, in good to excellent yields (up to 99%) and with excellent enantioselectivities (most cases >99%). Moreover, the reaction products are shown to give highly functionalized derivatives by stepwise systematic transformations. The experimental process involved the reaction of Isochroman-3-ol(cas: 42900-89-0).Quality Control of Isochroman-3-ol
The Article related to lactol nitroalkene stereoselective michael reaction enamine catalysis, functionalized lactone stereoselective preparation, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Quality Control of Isochroman-3-ol
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