On August 5, 2004, Groppi, Vincent Edward, Jr.; Rogers, Bruce Nelsen; Rudmann, Daniel Gregory published a patent.Name: (6-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol The title of the patent was Treatment of diseases with alpha-7 NACh receptor full agonists. And the patent contained the following:
The present invention relates to compositions and methods to treat diseases or conditions with alpha-7 nicotinic acetylcholine receptor (AChR) full agonists by decreasing levels of tumor necrosis factor-alpha and/or by stimulating vascular angiogenesis. The experimental process involved the reaction of (6-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol(cas: 280752-78-5).Name: (6-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol
The Article related to nicotinic acetylcholine receptor agonist quinuclidinylheteroarylamide cancer diabetes angiogenesis therapy, Pharmacology: Effects Of Nervous System- and Behavior-Affecting Drugs and Neuromuscular Agents and other aspects.Name: (6-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol
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