Brandhofer, Tobias; Stinglhamer, Martin; Derdau, Volker; Mendez, Maria; Poverlein, Christoph; Garcia Mancheno, Olga published an article in 2021, the title of the article was Easy access to drug building-blocks through benzylic C-H functionalization of phenolic ethers by photoredox catalysis.Category: alcohols-buliding-blocks And the article contains the following content:
A visible light-mediated photocatalyzed C-C-bond forming method for the benzylic C-H functionalization of phenolether containing synthetic building blocks based on a radical-cation/deprotonation strategy is reported. This method allows the mild, selective generation of benzyl radicals in phenolic complex mols. and drug-like compounds, providing new entries in synthetic and medicinal chem. The experimental process involved the reaction of H-Phg(4-OH)-OH(cas: 32462-30-9).Category: alcohols-buliding-blocks
The Article related to tyrosine methyl ester functionalization alkylation methyl acrylate photoredox catalysis, peptide synthesis alkylation photoredox catalysis reaction mechanism cyclic voltammetry and other aspects.Category: alcohols-buliding-blocks
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts