Month: October 2022

Sukuroglu, Ayca Aktas;Battal, Dilek;Kocadal, Kumsal;Sungur, Mehmet Ali;Cok, Ismet;Unlusayin, Irfan published 《Biomonitoring of bisphenol A, 4-nonylphenol, and 4-t-octylphenol in Turkish population: exposure and risk assessment》. The research results were published in《Environmental Science and Pollution Research》 in 2022.Category: alcohols-buliding-blocks The article conveys some information:

Biomonitoring studies are important tools to understand the effects of endocrine-disrupting compounds on human health. Up to now, there have been no biomonitoring and risk assessment studies conducted in Turkish population in which urinary bisphenol A (BPA), 4-nonylphenol (4-NP), and 4-t-octylphenol (4-t-OP) levels were measured simultaneously. The aim of this study is to measure urinary BPA, 4-NP, and 4-t-OP on Turkish population and conduct a risk assessment using urinary levels of chems. of interest. During the study, liquid chromatog. with tandem mass spectrometry (LC-MS/MS) was used to measure urinary levels of above-mentioned chems., and human biomonitoring was used as a risk assessment tool in 103 volunteers, living in Mersin Region, Turkey. Urinary BPA, 4-NP, and 4-t-OP were founded as 0.0079μg/g creatinine, 0.0177μg/g creatinine, and 0.0114μg/g creatinine, resp. The obtained estimated daily intakes (EDIs) were calculated as 0.095μg/kg bw/day, 0.041μg/kg bw/day, and 0.091μg/kg bw/day, for BPA, 4-NP, and 4-t-OP, resp. In conclusion, although no potential health risk due to BPA and 4-NP exposure was observed, there might be health risks associated with 4-t-OP exposure in the Turkish population.4-tert-Octylphenol (cas: 140-66-9) were involved in the experimental procedure.

4-tert-Octylphenol(cas: 140-66-9) has been used as a reference standard for the determination of the analyte in water samples using ultra-high-performance liquid chromatography/tandem mass spectrometry (UHPLC/MS/MS).Category: alcohols-buliding-blocks

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Xiaojie;Xu, Biping;Su, Weiping published 《Ni-Catalyzed Deoxygenative Borylation of Phenols Via O-Phenyl-uronium Activation》. The research results were published in《ACS Catalysis》 in 2022.HPLC of Formula: 599-64-4 The article conveys some information:

Herein, we report an efficient method for the Ni-catalyzed deoxygenative borylation of unprotected phenols and also demonstrate that this Ni-catalyzed phenolic C(sp²)-O transformation is applicable to the Suzuki-Miyaura-type and Heck-type cross-couplings of phenols. Investigations on the reaction intermediate have revealed that the achievement of general, mild deoxygenative cross-coupling reactions of phenols is ascribed to the conversion of phenols into the unusual O-phenyl-uroniums that feature active phenolic C(sp²)-O bonds. The Ni-complex intermediate resulting from an oxidative addition of a phenolic C(sp²)-O bond to monophosphine-supported Ni(0) catalyst was characterized and confirmed to be (PCy₃)₂Ni(Ar)(F) complex, offering exptl. evidence for the generally proposed C(sp²)-O oxidative addition step.4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) were involved in the experimental procedure.

4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.HPLC of Formula: 599-64-4 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

HPLC of Formula: 119-47-1In 2022, Zhan, Lingxi;Huang, Huanfang;Zhao, Shizhen;Wang, Zuwu;Zhang, Gan;Cheng, Hairong published 《Comparison of atmospheric polycyclic aromatic hydrocarbons (PAHs) over six years at a CAWNET background site in central China: Changes of seasonal variations and potential sources》. 《Chemosphere》published the findings. The article contains the following contents:

Total suspended particles (TSP) and gaseous samples were collected by using a high-volume sampler from March 2012 to March 2013 and Jan. 2018 to Jan. 2019 at a background site (Jinsha, JSH) in central China to study the chem. characteristics, seasonal variations, and potential sources of polycyclic aromatic hydrocarbons (PAHs). The average concentrations of ∑15PAHs were 24.55 ± 9.19 ng m-3 in 2012/2013 and 20.98 ± 9.77 ng m-3 in 2018/2019. Low-ring PAHs were more concentrated in gas phase while high-ring PAHs were prone into particle phase. The concentrations of PAHs in the two sampling years were high in winter but low in summer and autumn. The relationships between the gas concentrations of PAHs and temperature indicated that most PAHs were influenced by long-range atm. transport (LRAT) in 2012/2013 and in 2018/2019, excluding anthracene (Ant) and pyrene (Pyr) were partially affected by air-surface re-volatilization in 2012/2013. The source of atm. PAHs at JSH was similar in 2012/2013 and 2018/2019,which was mainly due to the LRAT of PAHs emitted from biomass/fossil fuel combustion in the northern area of JSH. From 2012/2013 to 2018/2019, there was no significant difference between the concentrations of PAHs in spring and winter, whereas the concentrations of PAHs decreased from 2012/2013 to 2018/2019 in summer. In all, the control of PAHs at the source region was partially effective from 2012/2013 to 2018/2019. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

HPLC of Formula: 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tong, Huiquan;Cao, Changwei;Du, Yanli;Liu, Yong;Huang, Wei published 《Ultrasonic-assisted phosphate curing: a novel approach to improve curing rate and chicken meat quality》 in 2022. The article was appeared in 《International Journal of Food Science and Technology》. They have made some progress in their research.Category: alcohols-buliding-blocks The article mentions the following:

The effects of ultrasound-assisted phosphate curing (UPC), phosphate curing (PC), and deionised water curing (DC) on the quality of chicken breast meat were investigated. The anal. of tissue sections, low-field NMR (LF-NMR), and headspace solid-phase microextraction gas-phase mass spectrometry (HS-SPME-GC-MS) of water distribution, myofibrillary structure, and volatile components of the meat samples were performed to reveal the mechanism. Also, the curing rate, water holding capacity (WHC), and shear force of meat were assessed. The results revealed that ultrasonic-assisted salting improved the meat salting rate, WHC, and tenderness by mech. destroying the muscle fiber structure, increasing the space between the muscle fiber bundles, promoting water migration and uniform distribution, and reducing water freedom in the treated samples. In addition, HS-SPME-GC-MS anal. revealed that PC significantly reduced the content of volatile flavor components in the chicken breast meat compared with DC (P < 0.05); however, the combination treatment with PC and ultrasonic curing could reconstruct the flavor loss caused by phosphate. Thus, our cumulative results suggest that the ultrasonic technol. may effectively assist the processing technol. in improving the quality of meat and reconstructing the flavor loss in meat products.2-Hexyl-1-decanol (cas: 2425-77-6) were involved in the experimental procedure.

2-Hexyl-1-decanol(cas: 2425-77-6) has been shown to inhibit the growth of b16 mouse melanoma cells, suggesting it may be useful for treating skin cancer.Category: alcohols-buliding-blocks This fatty acid also has transport properties and can form hydrogen bonds with other molecules.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

HPLC of Formula: 599-64-4In 2021, Shi, Junbin;Wang, Yubin;Bu, Qingqing;Liu, Binyuan;Dai, Bin;Liu, Ning published 《Cr-Catalyzed Direct ortho-Aminomethylation of Phenols》. 《Journal of Organic Chemistry》published the findings. The article contains the following contents:

A Cr-catalyzed strategy for the regioselective formation of Csp²-Csp³ bonds through the direct and efficient ortho-aminomethylation of N,N-dimethylanilines with phenols is reported. The approach showed excellent site selectivity at the ortho-position of phenols and accommodated broad substrate scope and functional group compatibility for both N,N-dimethylanilines and phenols. Mechanistic studies revealed that the direct ortho-aminomethylation between N,N-dimethylanilines and phenols occurred via an ionic mechanism. To complete the study, the researchers used 4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) .

4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.HPLC of Formula: 599-64-4 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wooding, Madelien;Rohwer, Egmont R.;Naude, Yvette published 《Determination of endocrine disrupting chemicals and antiretroviral compounds in surface water: A disposable sorptive sampler with comprehensive gas chromatography – Time-of-flight mass spectrometry and large volume injection with ultra-high performance liquid chromatography-tandem mass spectrometry》 in 2017. The article was appeared in 《Journal of Chromatography A》. They have made some progress in their research.Application of 80-46-6 The article mentions the following:

Many rural dwellers and inhabitants of informal settlements in South Africa are without access to treated water and collect untreated water from rivers and dams for personal use. Endocrine disrupting chems. (EDCs) have been detected in surface water and wildlife of South Africa. EDCs are often present in complex environmental matrixes at ultra-trace levels complicating detection thereof. We report a simplified multi-residue approach for the detection and quantification of EDCs, emerging EDCs, and antiretroviral drugs in surface water. A low cost (less than one US dollar), disposable, sorptive extraction sampler was prepared inhouse. The disposable samplers consisted of polydimethylsiloxane (PDMS) tubing fashioned into a loop which was then placed in water samples to concentrate EDCs and emerging pollutants. The PDMS samplers were thermally desorbed directly in the inlet of a GC, thereby eliminating the need for expensive consumable cryogenics. Comprehensive gas chromatog. coupled to time-of-flight mass spectrometry (GCxGC-TOFMS) was used for compound separation and identification. Linear retention indexes of EDCs and emerging pollutants were determined on a proprietary Crossbond phase Rtx^–CLPesticides II GC capillary column. In addition, large volume injection of surface water into an ultra-performance liquid chromatograph tandem mass spectrometer (UPLC-MS/MS) was used as complementary methodol. for the detection of less volatile compounds Large volume injection reduced tedious and costly sample preparation steps. Limits of detection for the GC method ranged from 1 to 98 pg/l and for the LC method from 2 to 135 ng/l. Known and emerging EDCs such as pharmaceuticals, personal care products and pesticides, as well as the antiretroviral compounds, efavirenz and nevirapine, were detected in surface water from South Africa at concentration levels ranging from 0.16 ng/l to 227 ng/l.4-tert-Amylphenol (cas: 80-46-6) were involved in the experimental procedure.

4-tert-acylphenol (cas:80-46-6) contains hydroxyl group.Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Application of 80-46-6

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Schroter, Ariane;Peter, Sonja;Mahler, Hanns-Christian;Zerr, Andreas;Danton, Ombeline;Chalus, Pascal;Koulov, Atanas V.;Huwyler, Jorg;Jahn, Michael published 《Identification of an Oxidizing Leachable from a Clinical Syringe Rubber Stopper》. The research results were published in《Journal of Pharmaceutical Sciences (Philadelphia, PA, United States)》 in 2021.Name: 2,5-Dimethyl-2,5-hexanediol The article conveys some information:

Leaching of toxic or reactive chems. from polymeric materials can adversely affect the quality and safety of biopharmaceuticals. It was therefore the aim of the present study to analyze leachables from a disposable clin. administration syringe using a polysorbate-containing surrogate solution and to assess their chem. reactivity. Anal. methods did include (headspace) GC-MS, Fourier-transform-IR spectroscopy, a ferrous oxidation-xylenol orange assay, and NMR anal. In the syringe leachables solution, the carcinogenic 1,1,2,2-tetrachloroethane (TCE) was detected in concentrations above the ICH M7-derived anal. evaluation threshold. TCE was shown to be an oxidation product of dichloromethane used during sample preparation Since TCE was only isolated from incubations with the contained rubber stopper, we hypothesized that a stopper-derived leachable acted as a reactive oxidant promoting this chem. reaction. Subsequently, the leachable was identified to be the polymerization initiator Luperox 101. Combining different anal. approaches led to the structural elucidation of a chem. reactive oxidant, which has the potential to interact and alter drug products. We conclude that chem. reactive compounds, such as the newly identified rubber stopper leachable Luperox 101, may be of concern and therefore should be routinely considered if a prolonged exposure of polymers with drug products can be anticipated. And 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) was used in the research process.

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.Name: 2,5-Dimethyl-2,5-hexanediol

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lee, Sangsuk;Straub, Anthony P. published 《Analysis of Volatile and Semivolatile Organic Compound Transport in Membrane Distillation Modules》 in 2022. The article was appeared in 《ACS ES&T Engineering》. They have made some progress in their research.HPLC of Formula: 140-66-9 The article mentions the following:

Membrane distillation (MD) is an emerging water treatment process that offers near-complete removal of nonvolatile contaminants. However, the transport of volatile compounds in the process is highly varied and poorly understood. In this work, we investigate the transport of a wide range of semivolatile and volatile compounds in membrane distillation (55 compounds total) allowing us to gain broad insights into the compound properties, system designs, and operating conditions that impact transport rates in direct-contact MD. We first use exptl. verified simulations to study the effects of different mol. properties on transport and show that the Henry’s constant and diffusion coefficient are the most important mol. properties in determining solute flux. We then study the transport resistances across MD membranes and find distinct transport regimes dominated by resistances associated with either diffusion through the membrane or boundary layers on either side of the membrane. Simulations of large-scale MD modules reveal the impact of membrane area, operating temperature, and crossflow velocity on the removal of contaminants. Finally, we comprehensively compare the removal of different classes of contaminants between MD and RO, finding that MD is more effective in removing small neutral compounds with low volatility. Overall, the results of this work demonstrate important compound properties and operating conditions that control volatile mass transport in MD. To complete the study, the researchers used 4-tert-Octylphenol (cas: 140-66-9) .

4-tert-Octylphenol(cas: 140-66-9) is a common environmental pollutant showing weak estrogenic effects.HPLC of Formula: 140-66-9 It has been shown to cause harm to vertebrate male reproductive systems.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Formula: C14H14O2《Iron-catalyzed one-pot synthesis of quinoxalines: transfer hydrogenative condensation of 2-nitroanilines with vicinal diols》 was published in 2021. The authors were Putta, Ramachandra Reddy;Chun, Simin;Lee, Seok Beom;Hong, Junhwa;Oh, Dong-Chan;Hong, Suckchang, and the article was included in《RSC Advances》. The author mentioned the following in the article:

Here, iron-catalyzed one-pot synthesis of quinoxalines via transfer hydrogenative condensation of 2-nitroanilines with vicinal diols was reported. The tricarbonyl (η⁴-cyclopentadienone) iron complex, which was well known as the Knolker complex, catalyzed the oxidation of alcs. and the reduction of nitroarenes, and the corresponding carbonyl and 1,2-diaminobenzene intermediates were generated in situ. Trimethylamine N-oxide was used to activate the iron complex. Various unsym. and sym. vicinal diols were applied for transfer hydrogenation, resulting in quinoxaline derivatives in 49-98% yields. A plausible mechanism was proposed based on a series of control experiments The major advantages of this protocol were that no external redox reagents or addnl. base was needed and that water is liberated as the sole byproduct. To complete the study, the researchers used rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .

Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Formula: C14H14O2) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Zhuo;Wang, Dan;Dao, Guohua;Shi, Qi;Yu, Tong;Guo, Fang;Wu, Guangxue published 《Environmental impact of the effluents discharging from full-scale wastewater treatment plants evaluated by a hybrid fuzzy approach》. The research results were published in《Science of the Total Environment》 in 2021.Related Products of 140-66-9 The article conveys some information:

Increasing attention is being paid to the environmental impacts of wastewater treatment plant (WWTP) effluent. In this study, comprehensive environmental impact analyses (EIAs) were performed for the secondary treatment processes, tertiary treatment processes, and entire plants at five full-scale WWTPs in Kunming, China. The EIAs took into account greenhouse gas (GHG) emissions, potential for the effluent to cause eutrophication, ecol. risks posed by endocrine disrupting compounds (EDCs) in treated effluent, and the risks posed by heavy metals in excess sludge. A comprehensive assessment toward environmental sustainability was performed using a fuzzy approach. The results indicated that the biol. treatment process made the largest contribution (>68% of the total) of the secondary treatment processes to GHG emissions and that electricity consumption made the largest contribution (>64% of the total) of the tertiary treatment processes to GHG emissions. Large numbers of EDCs were removed during the secondary treatment processes, but the potential ecol. risks posed by EDCs still require attention. High mercury concentrations were found in excess sludge. The plant that removed the largest proportion of pollutants and produced effluent posing the least ecol. risks gave the best comprehensive EIA performance. And 4-tert-Octylphenol (cas: 140-66-9) was used in the research process.

4-tert-Octylphenol(cas: 140-66-9) has been used as a reference standard for the determination of the analyte in water samples using ultra-high-performance liquid chromatography/tandem mass spectrometry (UHPLC/MS/MS).Related Products of 140-66-9

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts