Zaniol, Felipe team published research in Journal of Supercritical Fluids in 2020 | 24034-73-9

Application In Synthesis of 24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, 24034-73-9.

In general, the hydroxyl group makes alcohols polar. 24034-73-9, formula is C20H34O, Because of hydrogen bonding, alcohols tend to have higher boiling points than comparable hydrocarbons and ethers. Application In Synthesis of 24034-73-9

Zaniol, Felipe;Calisto, Jean F. F.;Cozzer, Gilberto;Ferro, Diego M.;Dias, Jonatas L.;Rodrigues, Luiz G. G.;Mazzutti, Simone;Rezende, Renan S.;Simoes, Daniel A.;Ferreira, Sandra R. S.;Dal Magro, Jacir;Oliveira, J. Vladimir research published 《 Comparative larvicidal effect of Pterodon spp. extracts obtained by different extraction methods》, the research content is summarized as follows. Pterodon spp. is a native Brazilian tree species of Fabaceae family, popularly known as sucupira. In the present study, the extraction methods of Soxhlet, supercritical fluid extraction (SFE) and ultrasound assisted extraction (UAE) were conducted at different conditions to recover compounds from “sucupira” with larvicidal activity against Aedes aegypti larvae. The influence of temperature and pressure on SFE with CO2 was compared to Soxhlet and UAE techniques, performed with hexane and ethanol as solvents. The use of ethanol as solvent provided better yields, but lower larvicidal activity. The extraction yields obtained with CO2 and hexane as solvents (non-polar) were similar, regardless the extraction method. Non-polar solvents showed better larvicidal activity with chances of having practical applications in fighting disease vectors. The chem. composition of these extracts presented as major components, trans-geranylgeraniol, germacrene-D-ol and caryophyllene, which showed to be responsible for the activity.

Application In Synthesis of 24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, 24034-73-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts