Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 16545-68-9, formula is C3H6O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , HPLC of Formula: 16545-68-9
Xue, Lian;Shi, Da-Hua;Harjani, Jitendra R.;Huang, Fei;Beveridge, Julia G.;Dingjan, Tamir;Ban, Kung;Diab, Sarah;Duffy, Sandra;Lucantoni, Leonardo;Fletcher, Sabine;Chiu, Francis C. K.;Blundell, Scott;Ellis, Katherine;Ralph, Stuart A.;Wirjanata, Grennady;Teguh, Silvia;Noviyanti, Rintis;Chavchich, Marina;Creek, Darren;Price, Ric N.;Marfurt, Jutta;Charman, Susan A.;Cuellar, Matthew E.;Strasser, Jessica M.;Dahlin, Jayme L.;Walters, Michael A.;Edstein, Michael D.;Avery, Vicky M.;Baell, Jonathan B. research published 《 3,3′-Disubstituted 5,5′-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity》, the research content is summarized as follows. A series of 3,3′-disubstituted 5,5′-bi(1,2,4-triazine) derivatives was synthesized and screened against the erythrocytic stage of Plasmodium falciparum 3D7 line. The most potent dimer, I, with an IC50 (50% inhibitory concentration) of 0.008 μM, had high in vitro potency against P. falciparum lines resistant to chloroquine (W2, IC50 = 0.0047 ± 0.0011 μM) and artemisinin (MRA1240, IC50 = 0.0086 ± 0.0010 μM). Excellent ex vivo potency of I was shown against clin. field isolates of both P. falciparum (IC50 = 0.022-0.034 μM) and Plasmodium vivax (IC50 = 0.0093-0.031 μM) from the blood of outpatients with uncomplicated malaria. Despite I being cleared relatively rapidly in mice, it suppressed parasitemia in the Peters 4-day test, with a mean ED50 value (50% ED) of 1.47 mg kg-1 day-1 following oral administration. The disubstituted triazine dimer I represents a new class of orally available antimalarial compounds of considerable interest for further development.
HPLC of Formula: 16545-68-9, Cyclopropanol is a cyclopropane in which a hydrogen atom is replaced by a hydroxy group. It is a member of cyclopropanes and an aliphatic alcohol.
Cyclopropanol is a useful research compound. Its molecular formula is C3H6O and its molecular weight is 58.08 g/mol. The purity is usually 95%.
Cyclopropanol is a cyclic organic compound that is synthesized from sodium hydroxide solution, nitrogen atoms, and carbonyl groups. Cyclopropanol has shown inhibitory effects on inflammatory bowel disease in rats. This drug also inhibits the production of hydrogen chloride and hydrochloric acid in the stomach, which can lead to ulcers. Cyclopropanol has been found to be effective against bowel diseases such as Crohn’s disease and ulcerative colitis. This drug has been shown to have strong antioxidant properties, which may be due to its ability to reduce hydroxyl radicals., 16545-68-9.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts