Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 16545-68-9, formula is C3H6O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Recommanded Product: Cyclopropanol
van der Westhuyzen, Renier;Winks, Susan;Wilson, Colin R.;Boyle, Grant A.;Gessner, Richard K.;Soares de Melo, Candice;Taylor, Dale;de Kock, Carmen;Njoroge, Mathew;Brunschwig, Christel;Lawrence, Nina;Rao, Srinivasa P. S.;Sirgel, Frederick;van Helden, Paul;Seldon, Ronnett;Moosa, Atica;Warner, Digby F.;Arista, Luca;Manjunatha, Ujjini H.;Smith, Paul W.;Street, Leslie J.;Chibale, Kelly research published 《 Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A Novel Antimycobacterial Class Targeting Mycobacterial Respiration》, the research content is summarized as follows. High-throughput screening of a library of small polar mols. against Mycobacterium tuberculosis led to the identification of a phthalimide-containing ester hit compound I, which was optimized for metabolic stability by replacing the ester moiety with a Me oxadiazole bioisostere. A route utilizing polymer-supported reagents was designed and executed to explore structure-activity relationships with respect to the N-benzyl substituent, leading to compounds with nanomolar activity. The front runner compound II from these studies was well tolerated in mice. A M. tuberculosis cytochrome bd oxidase deletion mutant (ΔcydKO) was hyper-susceptible to compounds from this series, and a strain carrying a single point mutation in qcrB, the gene encoding a subunit of the menaquinol cytochrome c oxidoreductase, was resistant to compounds in this series. In combination, these observations indicate that this novel class of antimycobacterial compounds inhibits the cytochrome bc1 complex, a validated drug target in M. tuberculosis.
16545-68-9, Cyclopropanol is a cyclopropane in which a hydrogen atom is replaced by a hydroxy group. It is a member of cyclopropanes and an aliphatic alcohol.
Cyclopropanol is a useful research compound. Its molecular formula is C3H6O and its molecular weight is 58.08 g/mol. The purity is usually 95%.
Cyclopropanol is a cyclic organic compound that is synthesized from sodium hydroxide solution, nitrogen atoms, and carbonyl groups. Cyclopropanol has shown inhibitory effects on inflammatory bowel disease in rats. This drug also inhibits the production of hydrogen chloride and hydrochloric acid in the stomach, which can lead to ulcers. Cyclopropanol has been found to be effective against bowel diseases such as Crohn’s disease and ulcerative colitis. This drug has been shown to have strong antioxidant properties, which may be due to its ability to reduce hydroxyl radicals., Recommanded Product: Cyclopropanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts