Owen, Robert M. team published research in Journal of Medicinal Chemistry in 2019 | 7748-36-9

Name: Oxetan-3-ol, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 7748-36-9, formula is C3H6O2, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Name: Oxetan-3-ol

Owen, Robert M.;Blakemore, David;Cao, Lishuang;Flanagan, Neil;Fish, Rebecca;Gibson, Karl R.;Gurrell, Rachel;Huh, Chan Woo;Kammonen, Juha;Mortimer-Cassen, Elisabeth;Nickolls, Sarah A.;Omoto, Kiyoyuki;Owen, Dafydd;Pike, Andy;Pryde, David C.;Reynolds, David S.;Roeloffs, Rosemarie;Rose, Colin;Stead, Clara;Takeuchi, Mifune;Warmus, Joseph S.;Watson, Christine research published 《 Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF-06372865)》, the research content is summarized as follows. The design, optimization, and evaluation of a series of novel imidazopyridazine-based subtype-selective pos. allosteric modulators (PAMs) for the GABAA ligand-gated ion channel are described. From a set of initial hits multiple subseries were designed and evaluated based on binding affinity and functional activity. As designing in the desired level of functional selectivity proved difficult, a probability-based assessment was performed to focus the project’s efforts on a single subseries that had the greatest odds of delivering the target profile. These efforts ultimately led to the identification of two precandidates from this subseries, which were advanced to preclin. safety studies and subsequently to the identification of the clin. candidate PF-06372865.

Name: Oxetan-3-ol, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts