Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 72824-04-5, formula is C9H17BO2, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Electric Literature of 72824-04-5
Lv, Leiyang;Qian, Huijun;Crowell, Anna B.;Chen, Shuming;Li, Zhiping research published 《 Pd/NHC-Controlled Regiodivergent Defluorinative Allylation of gem-Difluorocyclopropanes with Allylboronates》, the research content is summarized as follows. Controlling the selectivity of synthetically useful reactions has been a longstanding objective of organic chem. Authors report a regiodivergent synthetic protocol allowing access to diverse fluorinated 1,5-dienes through Pd/NHC-catalyzed ring-opening allylation of gem-difluorocyclopropanes. D. functional theory (DFT) calculations on regioselectivity-determining transition states provided critical insight into the design of the NHC ligand for switching regioselectivity. Consistent with the DFT predictions, N-heterocyclic carbene (NHC) ligands with bulky ortho substituents favored branched allylation, with the IHept ligand providing > 20:1 branched/linear regioselectivity. NHC ligands with less hindered ortho substituents such as IMes favored the thermodynamically more stable linear products. Authors were able to carry out late-stage modification of various complex mols. using this protocol. Authors ligand-controlled approach provides efficient access to regioisomeric fluorinated 1,5-dienes from the same starting materials and constitutes a valuable addition to the toolbox of diversity-oriented synthesis.
72824-04-5, Allylboronic acid pinacol ester is a useful research compound. Its molecular formula is C9H17BO2 and its molecular weight is 168.04 g/mol. The purity is usually 95%.
Allylboronic acid pinacol ester is an allylation reagent that is used to produce aldehydes from ketones. It reacts with water, yielding the desired product and formaldehyde as a byproduct. The reaction proceeds through a sequence of steps, in which the boronate ester first reacts with water to form an allylboronate ion and hydrogen gas. This intermediate then reacts with potassium t-butoxide to produce the desired allyl alcohol and potassium borohydride. Finally, the palladium complex catalyst reduces the carbonyl group of the starting material, converting it into an aldehyde. Allylboronic acid pinacol ester is commercially available as a white solid, but can also be synthesized from 2-chloro-5-pinacolylborane (pinacol) in high yield using catalytic cross coupling reactions., Electric Literature of 72824-04-5
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts