Sib, Anna; Gulder, Tobias A. M. published an article in 2018, the title of the article was Chemo-enzymatic Total Synthesis of Oxosorbicillinol, Sorrentanone, Rezishanones B and C, Sorbicatechol A, Bisvertinolone, and (+)-Epoxysorbicillinol.Product Details of 55743-13-0 And the article contains the following content:
The sorbicillinoids are a large family of fungal natural products, many of which possess highly challenging mol. architectures. Depending on their individual structures they exhibit strong biol. activities ranging from radical scavenging and anti-infective properties to cytotoxicity. Despite the resulting strong biomedical potential of these natural products and the interest of synthetic chemists owing to their fascinating structures, many sorbicillinoids are currently not synthetically accessible, thus hampering in-depth biol. characterization and structural diversification. By using recombinant oxidoreductase SorbC and readily accessible sorbicillin-type synthetic precursors, we have developed enantioselective, one-pot chemo-enzymic routes to a broad range of sorbicillinoids, thereby establishing total syntheses of oxosorbicillinol, sorrentanone, rezishanones B and C, sorbicatechol A, bisvertinolone, and (+)-epoxysorbicillinol. The experimental process involved the reaction of 2,4,6-Trihydroxy-3-methylbenzaldehyde(cas: 55743-13-0).Product Details of 55743-13-0
The Article related to sorbicillinoid chemoenzymic preparation, oxosorbicillinol chemoenzymic synthesis, sorrentanone chemoenzymic synthesis, rezishanone chemoenzymic synthesis, sorbicatechol a chemoenzymic synthesis, bisvertinolone chemoenzymic synthesis, epoxysorbicillinol chemoenzymic synthesis, biocatalysis, enzyme catalysis, natural products, sorbicillinoids, total synthesis and other aspects.Product Details of 55743-13-0
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