Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 24034-73-9, formula is C20H34O, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. Quality Control of 24034-73-9
Kumar Paul, Gobindo;Mahmud, Shafi;Aldahish, Afaf A.;Afroze, Mirola;Biswas, Suvro;Briti Ray Gupta, Swagota;Hasan Razu, Mahmudul;Zaman, Shahriar;Salah Uddin, Md.;Nahari, Mohammed H.;Merae Alshahrani, Mohammed;Abdul Rahman Alshahrani, Mohammed;Khan, Mala;Abu Saleh, Md. research published 《 Computational screening and biochemical analysis of Pistacia integerrima and Pandanus odorifer plants to find effective inhibitors against Receptor-Binding domain (RBD) of the spike protein of SARS-Cov-2》, the research content is summarized as follows. Although World Health Organization-approved emergency vaccines are available in many countries, the mortality rate from COVID-19 remains high due to the fourth or fifth wave and the delta variant of the coronavirus. Thus, an effective mechanistic investigation in treating this disease is urgently needed. In this work, we extracted phytochems. from two mangrove plants, Pistacia integerrima and Pandanus odorifer, assessing their potential actions against the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2. The antioxidant activities of Pistacia integerrima leaves and fruits were 142.10 and 97.13 μg/mL, resp., whereas Pandanus odorifer leaves and fruits were 112.50 and 292.71 μg/mL, resp. Furthermore, leaf extracts from both plants had lower cytotoxicity against Artemia salina than fruit extracts Gas chromatog.-mass spectrometry anal. revealed a total of 145 potential phytochems. from these extracts Three phytochems., 28-demethyl-beta-amyrone, 24-Noroleana-3,12-diene, and stigmasterol, displayed binding free energy values of – 8.3, -7.5, and – 8.1 Kcal/mol, resp., in complexes with the spike protein of SARS-CoV-2. The root-mean-square deviation, solvent-accessible surface area, radius of gyration, root-mean-square fluctuations, and hydrogen bonds were used to ensure the binding stability of the docked complexes in the atomistic simulation. Thus, wet-lab validations are necessary to support these findings.
Quality Control of 24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.
Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, 24034-73-9.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts