Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 533-73-3, formula is C6H6O3, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Name: Benzene-1,2,4-triol
He, Hang;Wang, Shizong;Wang, Jianlong research published 《 Degradation of 3-methylindole by ionizing radiation: Performance and pathway》, the research content is summarized as follows. Nitrogenous heterocyclic compounds (such as 3-methylindole) are common refractory organic pollutants in coal chem. wastewater, which cannot be effectively removed by conventional wastewater treatment processes. Therefore, advanced treatment process is required to eliminate them. In this study, ionizing radiation technol. was used to degrade 3-methylindole. The influencing factors, including absorbed doses (1, 2, 3 and 5 kGy), initial concentration of 3-methylindole (5, 10, 20 and 50 mg/L), and pH (3, 5, 7 and 9) on the degradation of 3-methylindole were investigated. The results showed that the removal efficiency of 3-methylindole was 96.2% when initial concentration was 20 mg/L, absorbed dose was 3 kGy, and pH was 3. The quenching experiments indicated that hydroxyl radicals, hydrated electrons and hydrogen radicals contributed to 3-methylindole degradation The intermediate products during the process of 3-methylindole degradation were identified by LC-MS anal., including anthranilic acid (2-aminobenzoic acid), gentisic acid (2-hydroxybenzoic acid) and 1,2,4-trihydroxybenzene (benzene-1,2,4-triol). The possible degradation pathway was proposed based on the identified products. The toxicity of 3-methylindole and its intermediates were predicted by using ECOSAR, suggesting that the intermediate products of 3-methylindole degradation had lower toxicity than 3-methylindole. This study provided an insight into 3-methylindole degradation by ionizing radiation.
Name: Benzene-1,2,4-triol, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., 533-73-3.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts