Zmyslowski, Adam; Szterk, Arkadiusz published the artcile< Oxysterols as a biomarker in diseases>, Related Products of 434-16-2, the main research area is review atherosclerosis Alzheimers disease progression oxysterol biomarker diagnosis; 24(S)-hydroxycholesterol; 27-hydroxycholesterol; Atherosclerosis; Biomarker; Neurodegenerative diseases; Oxysterols.
A review. Cholesterol is one of the most important chem. substances as a structural element in human cells, and it is very susceptible to oxidation reactions that form oxysterol. Oxysterols exhibit almost the exact structure as cholesterol and a cholesterol precursor (7-dehydrocholesterol) with an addnl. hydroxyl, epoxy or ketone moiety. The oxidation reaction is performed via an enzymic or non-enzymic mechanism. The wide array of enzymic oxysterols encountered in the human body varies in origin and function. Oxysterols establish a concentration equilibrium in human body fluids. Disease may alter the equilibrium, and oxysterols may be used as a diagnostic tool. The current review presents the possibility of using non-enzymic oxysterols and disturbances in enzymic oxysterol equilibrium in the human body as a potential biomarker for diagnosing and/or monitoring of the progression of various diseases.
Clinica Chimica Acta published new progress about Alzheimer disease. 434-16-2 belongs to class alcohols-buliding-blocks, and the molecular formula is C27H44O, Related Products of 434-16-2.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts