In 2022,Zhu, Huilong; Zhou, Qianqian; Liu, Na; Xing, Junhao; Yao, Weijun; Dou, Xiaowei published an article in Advanced Synthesis & Catalysis. The title of the article was 《Relay Rhodium(I)/Acid Catalysis for Rapid Access to Benzo-2H-Pyrans and Benzofurans》.Formula: C6H7BO3 The author mentioned the following in the article:
Relay rhodium(I)/Broensted acid catalysis for tandem arylation-cyclization reaction was developed. Chemodivergent syntheses of benzo-2H-pyrans I [R = H, 6-Cl, 6-Me; R1 = n-Pr, cyclopropyl, i-BuCH2, PhCH2, PhCH2OCH2; R2 = Ph, R3 = Me, n-Pr, Ph, 4-MeOC6H4, etc.; R2 = H, R3 = H, Et, Ph; R2R3 = (CH2)4, o-C6H4-o-C6H4; etc.] and benzofurans II (R = H, 4-F, 5-Me, 6-F; R1 = Ph, 4-MeOC6H4, 2-thienyl, etc.; R2 = H, Me, n-pentyl, Ph; R3 = H) from propargyl alcs. R1CCCR2R3OH and R-substituted ortho-hydroxylated arylboronic acids were achieved under this relay catalysis system. An ortho-hydroxy effect on changing the chemoselectivity and reactivity was observed In the experiment, the researchers used many compounds, for example, 2-Hydroxyphenylboronic acid(cas: 89466-08-0Formula: C6H7BO3)
2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Formula: C6H7BO3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts