In 2018,Zhao, Jingming; Bachmann, Daniel G.; Lenz, Markus; Gillingham, Dennis G.; Ward, Thomas R. published 《An artificial metalloenzyme for carbene transfer based on a biotinylated dirhodium anchored within streptavidin》.Catalysis Science & Technology published the findings.Electric Literature of C7H6O3 The information in the text is summarized as follows:
Artificial metalloenzymes that incorporate a biotinylated dirhodium core embedded within engineered streptavidin (Sav hereafter) variants are reported. The resulting biohybrid catalyzes the carbene insertion in C-H bonds and olefins. Chem.- and genetic optimization allows to modulate the catalytic activity of the artificial metalloenzymes that are shown to be active in the periplasm of E. coli (up to 20 turnovers). The results came from multiple reactions, including the reaction of 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Electric Literature of C7H6O3)
3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is used as a building block in the synthesis of more complex structures. It is also used in the synthesis of terbutaline, which is an important bronchodilator.Electric Literature of C7H6O3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts